About
- Rooted in Our Community St. Dominic is a Catholic, comprehensive, coeducational high school with deep ties to our area parishes and communities.
- Our Campus, Our Home Our 50-acre campus is among the largest of any Catholic high school in the St. Louis area.
Admissions
- Apply to St. Dominic Learn more about how to join the St. Dominic family.
- Visit Us on Campus Experience life at St. Dominic firsthand with a shadow visit or personal tour.
Academics
- College Preparatory Education With dual credit and AP coursework, individual college guidance and more, 99% of our graduates continue to higher education.
- Leadership in STEM We offer interactive broadcasting coursework, as well as 11 hands-on courses in computer science, engineering, aerospace and biomedical sciences through Project Lead the Way.
Faith
- Living Our Faith Prayer is an essential part of life at St. Dominic, whether in classes or practices, during Adoration or at all-school Masses.
- Walking with Christ Students reflect and grow through retreats at each stage of the high school experience.
Student Life
- Explore Your World Our 40 clubs and organizations offer new experiences and leadership opportunities.
- A Day in the Life St. Dominic is more than a school – it’s a second home. See what a typical day might have in store for you.
Arts
- Take a Bow Students can shine onstage or behind the scenes in the Crusader Players' four annual stage productions.
- Center Stage Take a peek at the 500-seat Amy Dickherber Performing Arts Center.
Athletics
- Crusader Spirit The St. Dominic Crusaders compete in 24 varsity sports.
- Home of the Crusaders Tour our athletic facilities, from Crusader Stadium to our state-of-the-art fitness center.
Giving
- Called to Lead Join us in making the 42,000-sq.-ft. Center for the Sciences a reality.
- Ways to Give Explore our many giving options to find the best fit for you and your family.

In This Section

History

St. Dominic’s roots extend to 1929, when Assumption High School opened in O’Fallon. In 1962, the Archdiocese of St. Louis established St. Dominic as a regional high school serving St. Charles, Lincoln and Warren counties.

Our name honors St. Dominic Guzman, patron of the Dominican Sisters of Sparkill who answered Cardinal Ritter’s call to lead the school. Longtime librarian Sr. Jeanne Margaret Stoltz, OP, was the final Dominican sister to teach at St. Dominic, retiring in 2009.

The current St. Dominic Drive campus opened in 1963, with major additions in 2000, 2005, 2010 and 2022. Today, our campus spans over 50 acres, with 181,775 square feet of educational facilities.